Recent Publications

Molina Lopez E, Kabanova A, Winkel A, Franze K, Palacios IM, and Martín-Bermudo MD. (2023) Constriction imposed by basement membrane regulates developmental cell migration. PLoS Biol. Jun 28;21(6):e3002172. doi: 10.1371/journal.pbio.3002172.eCollection.

Santa-Cruz Mateos C, Valencia-Expósito A, Palacios IM, and Martín-Bermudo MD (2020). Integrins regulate epithelial cell shape by controlling the architecture and mechanical properties of basal actomyosin networks. PLoS Genet. Jun 1;16(6):e1008717. doi: 10.1371/journal.pgen.1008717

Drechsler M, Lang LF, Al-Khatib L, Dirks H, Burger M, Schönlieb CB, Palacios IM (2020). Optical flow analysis reveals that Kinesin-mediated advection impacts on the orientation of microtubules. Mol Biol Cell. Jun 1;31(12):1246-1258. doi: 10.1091/mbc.E19-08-0440.

Francis D, Chanana B, Fernandez B, Gordon B, Mak T, and Palacios IM (2019). YAP/Yorkie in the germline modulates the age-related decline of germline stem cells and niche cells. PLoS One. Apr 3;14(4).

Drechsler M, Giavazzi F, Cerbino R, Palacios IM. Active diffusion and advection in Drosophila oocytes result from the interplay of actin and microtubules.  Nature Communications. 8, 1520 (2017).  doi:10.1038/s41467-017-01414-6

Vicente-Crespo M, Martín-Bermudo MD, and Palacios IM (2020). The humble fruit fly is helping the African science community to thrive. Nature Reviews MCB doi.10.1038/s41580-020-00283-0

Ng BF, Selvaraj GK, Santa-Cruz Mateos C, Grosheva I, Alvarez-Garcia I, Martín-Bermudo MD and Palacios IM (2016) Alpha-Spectrin and Integrins act together to regulate actomyosin and columnarization, and to maintain a monolayered follicular epithelium. Development. 2016 Apr 15;143(8):1388-99.

Saavedra P, Brittle A, Palacios IM, Strutt D, Casal J and Lawrence PA (2016). Planar cell polarity: the Dachsous-Fat system contributes differently to the embryonic and larval stages of Drosophila. Biology open. 2016;5(4):397-408.

Other Publications

Palacios IM (2014). Hop on hop off: polysomes take a tour of the cell on endosomes.J. Cell Biology.2014 Feb 3;204(3):287-9.

Gómez-Lamarca MJ, Cobreros-Reguera L, Ibáñez-Jiménez B,Palacios IM and Martín-Bermudo MD. (2014). Integrins regulate epithelial cell differentiation by modulating Notch activity.J. Cell Science.2014 Nov 1;127(21):4667-78.

Saavedra P, Vincent JP, Palacios IM, Lawrence PA, Casal J. Plasticity of both planar cell polarity and cell identity during the development of Drosophila. Elife. 2014 Feb 11;3:e01569. doi: 10.7554/eLife.01569.

Palacios IM. Hop-on hop-off: Polysomes take a tour of the cell on endosomes. J Cell Biol. 2014 Feb 3;204(3):287-9. doi: 10.1083/jcb.201401019.

Williams LS, Ganguly S, Loiseau P, Ng BF, and Palacios IM. The auto-inhibitory domain and the ATP-independent microtubule-binding region of Kinesin Heavy Chain are major functional domains for transport in the Drosophila germline. Development. 2014 Jan;141(1):176-86. doi: 10.1242/dev.097592. Epub 2013 Nov 20.

Palacios IM. Nonsense mediated RNA Decay (2012). Briefings in Functional Genomics. Nov 11 (Epub ahead of print).

Ganguly S*, Williams LS*, Palacios IM**, and Goldstein RE** (2012) “Cytoplasmic streaming in Drosophila oocytes varies with kinesin activity and correlates with the microtubule cytoskeleton architecture”. PNAS.18;109(38):15109-14.

* Contributed equally as first authors.
** Contributed equally as senior and corresponding authors

Avery P, Vicente-Crespo M, Francis D, Nashchekina O, Alonso CR, and Palacios IM (2011) “Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner”. RNA 17: 624-638.
Described as “of outstanding interest” by Hwang, J and Maquat, LE, Curr. Opin. Genet Dev. 2011; 21(4):422-30.

Vicente-Crespo M and Palacios IM (2010) “Nonsense-mediated mRNA decay and Development:shoot the messenger to survive?” Biochemical Society Transactions Dec;38(6):1500-5.

Loiseau P, Davies T, Williams LS, Mishima M, and Palacios IM. (2010) “Drosophila Pat1 is required for Kinesin-1 to transport cargo and to maximize its motility”. Development 137, 2763-2772

Meignin C, Alvarez-Garcia I, Davis I, Palacios IM. (2007). "The salvador-warts-hippo pathway is required for epithelial proliferation and axis specification in Drosophila". Current Biology. Nov; 17(21):1871-8. Dispatch in Current Biology 17, Issue 23 (2007)

Palacios IM. (2007). "How does an mRNA find its way? Intracellular localisation of transcripts". Seminars in Cell and Developmental Biology. Apr;18(2):163-170.

Palacios IM, Gatfield D, St Johnston D and Izaurralde E (2004). An eIF4AIII-containing complex required for mRNA localisation and nonsense-mediated mRNA decay. Nature 427:753-757. News and Views, Nature Cell Biology 6, 285 - 287 (2004)

Macchi P., Kroening S., Palacios IM., Baldassa S., Grunewald B., Ambrosino C., Lupas A., St Johnston D. and Kiebler M. (2003). Barentsz, a new component of the Staufen-containing ribonucleoprotein particles in mammalian cells, interacts with Staufen in a RNA-dependent manner. Journal of Neuroscience 23(13):5778-5788.

Palacios IM. (2002). RNA Processing: Splicing and the cytoplasmic localisation of mRNA. Current Biology 12:50-52.

Palacios IM. and St Johnston D. (2002). Kinesin light chain-independent function of the Kinesin heavy chain in cytoplasmic streaming, and posterior localisation in the Drosophila oocyte. Development 129(23):5473-5485.

Benton, R, Palacios IM. and St Johnston D. (2002). Drosophila 14-3-3/PAR-5 is an essential mediator of PAR-1 function in axis formation. Developmental Cell 3(5):659-671.

Palacios, IM. and St Johnston D. (2001). Getting the Message Across: The Intracellular Localization of mRNAs in Higher Eukaryotes. Annual Review of Cell and Developmental Biology 17:569-614.

van Eeden, FJM., Palacios IM., Petronczki M., Weston M., and St Johnston D. (2001). Barentsz is essential for the posterior localization of oskar mRNA and co-localizes with it to the posterior pole. Journal of Cell Biology 154:511-523.

Wagner C., Palacios I., Jaeger L., St Johnston D., Ehresmann B., Ehresmann C., and Brunel C. (2001). Dimerization of the 3'UTR of bicoid mRNA Involves a Two-step Mechanism. Journal of Molecular Biology 313(3):511-524.

Palacios, I. and Izaurralde, E. (2000). RNA transport and localisation. Encyclopedia Life Sciences, (Nature & MacMillan Publishers) (http://www.els.net)

Dingwall, C. and Palacios, I. (1997). in vitro systems for the reconstitution of UsnRNP and protein nuclear import. Methods in Cell Biology 53:517-543.

Palacios, I., Hetzer, M., Adam, S.A. and Mattaj, I.W. (1997). Nuclear import of U snRNPs requires importin β. The EMBO Journal 16: 6783-6792.

Perales, B., De La Luna, S., Palacios, I., and Ortin, J. (1996). Mutational analysis identifies functional domains in the Influenza A virus PB2 polymerase subunit. Journal of Virology 70: 1678-1686.

Palacios, I., Weis, K., Klebe, C., Mattaj, I.W., and Dingwall, C. (1996). RAN/TC4 mutants identify a common requirement for U snRNP and protein import into the nucleus. Journal of Cell Biology 133: 485-494.

Palacios, I. and Izaurralde, E. (1996). Nucleocytoplasmic transport over the Garda Lake. Trends in Cell Biology 7:81-83.

Boelens, W.C., Palacios, I., and Mattaj, I.W. (1995). Nuclear retention of RNA as a mechanism for localization. RNA 1:273-283.

Outreach Publications

Vicente-Crespo M, Palacios IM, and Martín-Bermudo MD (2022). Equal contribution. DrosAfrica: una Puerta hacia una investigación biomedica productiva en África. Meridiano Cero, Año 2.

Vicente-Crespo M, Martín-Bermudo MD, and Palacios IM (2020). The humble fruit fly is helping the African science community to thrive. Nature Reviews MCB doi.10.1038/s41580-020-00283-0

Martin-Bermudo MD, Gebel L and Palacios IM (2017). DrosAfrica: Building an African biomedical research community using Drosophila. Seminars in Cell and Developmental Biology. DOI: 10.1016/j.semcdb.2017.08.044

Vicente Crespo M, Muñoz Descalzo S, Weil T, Martin-Bermudo D, and Palacios I (2016); Workshop-Based Training for Capacity Building: Using Drosophila to Bring Research Skills to Africa; FASEB Journal 30 (1) suppl.663.2.

MD Martín-Bermudo, I. Palacios, M. Vicente Crespo, A. Gonzalez-Reyes, S. Muñoz Descalzo, and T. Weil (2013). DROSOPHILA IN BIOMEDICAL RESEARCH: AFFORDABLE AND IMPACTING. 6th International Conference of Education, Research and Innovation, Spain.

Baden T, Palacios I, Vicente M, Martin-Bermudo D, Yusuf S, and Prieto Godino L (2012). Higher Education in the Developing World: Drosophila Neurogenetics, Uganda. INTED2012, Valencia, Spain.

Baden T, Palacios I, Vicente M, Martin-Bermudo D, Yusuf S, and Prieto Godino L (2011). Breaking the Wall of Global Inequality in Higher Education. Falling Walls Conference, Berlin, Germany